Fig. 8. Effect of SST14 on SSTR receptor expression under conditions of glucose and serum deficiency. Sstr mRNA expression was assessed in MIN6 beta cells by qPCR following pre-treatment with 1 μmol/l SST14 for 48h (10% FBS) followed by 48h exposure to 5.5 mmol/l glucose (Glu, 2% FBS) or 2% FBS alone with our without SST14. Panels A-D show results for Sstr 1, 2, 3, and 5, respectively. *P<0.05 vs 10% FBS control, ^∆P<0.05 vs 2% FBS (one way ANOVA and Bonferroni's multiple comparisons test). Data expressed as means ± SEM of four separate experiments.